A Sensitive Electrochemical Sensor for Determination of Imipramine in Urine Sample Using Carbon Ionic Liquid Electrode Modified With Montomorillonite Nanoclay

Authors

  • Elham Eslami Department of Chemistry, Kazerun Branch, Islamic Azad University, Kazerun, Iran
  • Fatemeh Farjam Department of Chemistry, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran
Abstract:

We used an effective electrochemical sensor for the determination of imipramine at pH 7.2 using a carbon nanocomposite electrode. The electrode has been designed by incorporation of montmorillonite nanoclay into the carbon ionic liquid electrode. The high sensitivity of 1.714 μA (μM)-1, two linear calibration ranges of 0.1–2 μM and 2-40 μM, and detection limit of 19 nM were achieved. The relative standard deviations (RSDs) were 2.73% (n=7, 2 μM), 2.97% (n=4, 2 μM), respectively. Thus, this modified electrode was further applied to the determination of imipramine in urine sample.

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Journal title

volume 5  issue 1

pages  165- 171

publication date 2017-12-01

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